Methods for determining whether a patient will achieve a response after radiation therapy - Techno Market

Offre n°2698
Methods for determining whether a patient will achieve a response after radiation therapy

L'innovation

The invention relates to methods for determining whether a patient will achieve a response after radiation therapy.
In particular, the innovation relates to a method for determining whether a patient suffering from a cancer will achieve a response after radiation therapy comprising the steps of :

1. determining the level of ceramide in a first blood sample obtained from the patient before radiation therapy
2. determining the level of ceramide in a second blood sample obtained from the patient during or just after radiation therapy

The innovation allows to compare the level determined at step 1. with the level determined at step 2 and concluding that
- the patient will achieve response when the level determined at step 2. is higher than the level determined at step 1.
or concluding that
- the patient will not achieve a response when the level determined at step 2. is lower than the level determined at step 1.

Ses bénéfices

  • Improvement of radiotherapy treatment
  • Adaptation of treatment vs response

Ses applications

  • Monitoring of radiotherapy protocol : in particularly in the context of hypofractionated radiation therapy
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Stade de développement

  • IN VIVO - Preuve de concept

Laboratoire de recherche

UMR_S 1232 - CRCINA

Équipe de recherche

Equipe 14 : Endothelium radiobiology and targeting

Propriété intellectuelle associée

EP : EP14305764 - filed on the 05-23-2014
WO - CA,EP,JP,US

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